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Regenerative and Degenerative Biology

Regeneration is the renewal of degenerated or lost cells, tissues or organs within an organism. Such regenerative processes are mainly based on the action of specific stem or progenitor cells that possess the capacity to proliferate and differentiate into the required cell-types. In Dresden the mechanisms of regeneration and stem cell function are studied to understand general principles of cellular and tissue repair with the aim to use this knowledge to develop novel therapies. Diverse strategies for in depth genetic, molecular and cellular analysis are used to dissect fundamental pathways of tissue regeneration. Animals with high regenerative capacities are utilized to understand intrinsic mechanisms of regeneration as models to induce tissue repair also in mammals. Additionally, the controlled expansion and directed differentiation of stem cells towards specific target cell-types is assessed to develop cell replacement strategies for currently incurable diseases.

© Sandoval Guzmán Group

Research Groups

© CRTD

Marius Ader Group

TUD CRTD Development of cell-based therapies for the treatment of retinopathies

Michael Bachmann Group

HZDR Tumorimmunology

Michael Brand Group

TUD CRTD, TUD BIOTEC, TUD PoL Development and Regeneration of the Vertebrate Brain

Currently Recruiting (call is closed)

Björn Falkenburger Group

TUD Medical Campus Cell biology of neurodegenerative diseases

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Anthony Gavalas Group

TUD PLID Stem Cells in Pancreas Development and Disease

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Mike Karl Group

DZNE, TUD CRTD Unraveling mechanisms of neuronal degeneration and regeneration in the retina

Caghan Kizil Group

DZNE, TUD CRTD Mechanisms of Induced Plasticity of the Brain

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Natalia Rodríguez Muela Group

DZNE, CRTD Selective neuronal vulnerability in neurodegenerative diseases

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Tatiana Sandoval Guzmán Group

TUD CRTD Vertebrate tissue repair and regeneration

Currently Recruiting (call is closed)

Michael Sieweke Group

TUD CRTD Stem Cell and Macrophage Biology

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Maximina Yun Group

TUD CRTD Regeneration of Complex Structures in Adult Vertebrates