Dresden International Graduate School for Biomedicine and Bioengineering

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Regenerative Biology

Regeneration is the renewal of degenerated or lost cells, tissues or organs within an organism. Such regenerative processes are mainly based on the action of specific stem or progenitor cells that possess the capacity to proliferate and differentiate into the required cell-types. In Dresden the mechanisms of regeneration and stem cell function are studied to understand general principles of cellular and tissue repair with the aim to use this knowledge to develop novel therapies. Diverse strategies for in depth genetic, molecular and cellular analysis are used to dissect fundamental pathways of tissue regeneration. Animals with high regenerative capacities are utilized to understand intrinsic mechanisms of regeneration as models to induce tissue repair also in mammals. Additionally, the controlled expansion and directed differentiation of stem cells towards specific target cell-types is assessed to develop cell replacement strategies for currently incurable diseases.

Image © Michael Brand Group

Research Groups

© CRTD

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Marius Ader Group

TUD CRTD

Development of cell-based therapies for the treatment of retinopathies

Michael Bachmann Group

HZDR

Tumorimmunology

Michael Brand Group

TUD CRTD, TUD BIOTEC

Development and Regeneration of the Vertebrate Brain

© CRTD

Mike Karl Group

DZNE, TUD CRTD

Unraveling mechanisms of neuronal degeneration and regeneration in the retina

© CRTD

Caghan Kizil Group

DZNE, TUD CRTD

Molecular mechanisms of stem cell plasticity and regenerative neurogenesis in adult zebrafish brain

© CRTD

Michell Reimer Group

TUD CRTD

Regulation of developmental and regenerative processes in the spinal cord

© CRTD

Tatiana Sandoval Guzmán Group

TUD CRTD

Vertebrate tissue repair and regeneration

Claudia Waskow Group

TUD MTZ

Regeneration in Hematopoiesis